Dissolving microneedle patch is a substrate of polymers that dissolve in vivo blended with active
ingredients and molded into the shape of fine needles. The patch form can be placed directly on
the skin. These needles are then processed into a patch to produce a transdermal dosage form.
When the patch is placed on the skin, the needles penetrate through the skin’s barrier function and
dissolve directly inside the skin, delivering the active ingredients far more efficiently than simple
topical application.
The diameter (thickness) of the needle tip is one-tenth or less than the outer diameter of an intradermal
injection needle, causing virtually no pain when placed on the skin and making the patch a minimally
invasive DDS (Drug Delivery System).Needles measuring several tens to hundreds of micrometers in length.
A dissolving microneedle patch infused with age fighting retinol, peptides, and vitamin C to smooth
the appearance of fine lines and wrinkles. Each patch contains many self-dissolving microneedles
that create tiny pathways for age-fighting ingredients. Good for crow’s feet, smile lines, forehead wrinkles
and eye wrinkles. The microneedle technologies, initially meant for medicine, are now opening up a new
era in cosmetic development.
The depth of delivery of active substances, unattainable for usual beauty products, and microneedle
dermal stimulation allow to achieve amazing clinical results for skin’s youth and beauty with
lotus’s stylish approach making it a rare example of alliance between science and beauty.
- Ability to manipulate The drug formulation; suspension, powder,…
- pain-free, non-invasive, convenient route for reagent administration and delivery
- long-term nourishing skin
Why Dissovable Microneedle Array
- Patient self-administration
- penetration depthPrecise control of Effortless and painless
- Direct and controlled delivery
Features of high-precision molded microneedles
Optimal needle shapes by compliances with regional regulations
Strong needles resistant to breakage prior to use
Consistent molding quality in mass production
High-density design of 200 or more needles per square centimeter
Low-temperature drying process to prevent denaturation of the
active ingredients
Application of Microneedles to Immunobiologicals drugs delivery
Microneedles have an edge over the other methods due to lack of pain. such as influenza vaccine, hepatitis B vaccine, flavivirus vaccine etc.
Application of Microneedles to Biopharmaceuticals drugs delivery
Insulin, heparin, and growth hormones, parathyroid hormone, human growth hormone,
desmopressin can be delivered by microneedles.
Application of Microneedles to painkillers and local Anastasia drugs delivery
Diclofenac, lidocaine, naltrexone, doxetaxel etc can be administered via microneedles.
Cosmetic patch Ingredients:
Hyaluronic acid: a component of the skin that is involved in its regeneration, hydrodynamics and cell proliferation. This accounts for the moisturizing and antiaging properties of hyaluronic acid in case its lack is compensated from the outside. The microneedles will deliver hyaluronic acid straight to the basement membrane of the skin, which is beyond reach for conventional creams.
Vitamin C: Visibly brightens skin and supports healthy collagen production.
Peptides: Supports collagen and reduces the look of fine lines and wrinkles.
Clinical Results for cosmetic patch:
In the early hours: Improved the appearance of their fine lines and wrinkles
After one month of use: Wrinkles and fine lines were less noticeable and participants said the
product worked faster than any product they’ve used.